BDBM406380 2-((3S,4R or 3R,4S)-3-Benzyl-4-hydroxychroman-7-yl)-N-(cyclopropylsulfonyl)benzamide::US10336733, Example 24

SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1ccccc1C(=O)NS(=O)(=O)C1CC1

InChI Key InChIKey=WWSYXSJWLOBBSL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406380   

TargetLeukotriene B4 receptor 1(Human)
Merk Sharp & Dohme

US Patent
LigandPNGBDBM406380(2-((3S,4R or 3R,4S)-3-Benzyl-4-hydroxychroman-7-yl...)
Affinity DataEC50:  17nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent