BDBM406110 1-(trans-5',6'-difluoro-2'- hydroxy-2',3'- dihydrospiro[cyclopropane- 1,1'-inden]-3'-yl)-3-(3- methoxy-4-methyl-1-phenyl- 1H-pyrazol-5-yl)urea::US10351575, Example 62

SMILES COc1nn(c(NC(=O)NC2[C@H](O)C3(CC3)c3cc(F)c(F)cc23)c1C)-c1ccccc1

InChI Key InChIKey=VWBULDXTNIPXJP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406110   

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM406110(1-(trans-5',6'-difluoro-2'- hydroxy-2',3'- dihydro...)
Affinity DataIC50: 100nMAssay Description:TrkA binding activity was determined in a TrkA LanthaScreen Eu Kinase Binding Assay. 5 nM His-tagged recombinant human TrkA (6HIS tagged cytoplasmic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details
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