BDBM405830 US10351548, Compound DF9

SMILES Fc1ccc(Cn2cccc(C(=O)NCCCC(=O)Nc3ccc4NC(=O)C(=Cc5cccs5)c4c3)c2=O)cc1F

InChI Key InChIKey=UQXYMWSKHOCOJF-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405830   

Target3-phosphoinositide-dependent protein kinase 1(Human)
International Society For Drug Development

US Patent

LigandBDBM405830(US10351548, Compound DF9)Copy SMILESCopy InChI

Affinity DataIC50: 5.88E+3nMAssay Description:Factor IX is a key component of the plasma system that forms a fibrin clot at a site of vascular injury. The activity of Factor IXa is measured by mo...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/12/2020
Entry Details
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Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
University of Pisa

Curated by ChEMBL

LigandBDBM405830(US10351548, Compound DF9)Copy SMILESCopy InChI

Affinity DataIC50: 5.88E+3nMAssay Description:Inhibition of recombinant full length human His-tagged PDK1 expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
Copy Entry DOIPubMed
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