BDBM405092 1-{2-fluoro-4-[4-({[3- (trifluoromethoxy)phenyl]methyl} carbamoyl)-1H-1,2,3-triazol-1-yl] butyl}-N-{[6-(trifluoromethyl) pyridin-2-yl]methyl}-1H-1,2,3- triazole-4-carboxamide::US10344025, Example 436::US11370786, Example 436

SMILES FC(CCn1cc(nn1)C(=O)NCc1cccc(OC(F)(F)F)c1)Cn1cc(nn1)C(=O)NCc1cccc(n1)C(F)(F)F

InChI Key InChIKey=RNOCQKSVGRZRAC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405092   

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM405092(US10344025, Example 436 | 1-{2-fluoro-4-[4-({[3- (...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM405092(US10344025, Example 436 | 1-{2-fluoro-4-[4-({[3- (...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent