BDBM405068 1-[3-fluoro-4-(4-{2-[2-fluoro-5- (trifluoromethoxy)phenyl]acetamido}- 1H-1,2,3-triazol-1-yl)butyl]-N-{[6- (trifluoromethyl)pyridin-3-yl]methyl}- 1H-1,2,3-triazole-4-carboxamide::US10344025, Example 412::US11370786, Example 412

SMILES FC(CCn1cc(nn1)C(=O)NCc1ccc(nc1)C(F)(F)F)Cn1cc(NC(=O)Cc2cc(OC(F)(F)F)ccc2F)nn1

InChI Key InChIKey=UCAREPCUKWFFEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405068   

TargetGlutaminase kidney isoform, mitochondrial(Human)
University Of Texas

US Patent
LigandPNGBDBM405068(US10344025, Example 412 | 1-[3-fluoro-4-(4-{2-[2-f...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
University Of Texas

US Patent
LigandPNGBDBM405068(US10344025, Example 412 | 1-[3-fluoro-4-(4-{2-[2-f...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
US Patent