BDBM405056 1-(3-fluoro-4-{4-[2-(6-methylpyridin- 3-yl)acetamido]-1H-1,2,3-triazol-1- yl}butyl)-N-{[4- (trifluoromethyl)pyridin-2-yl]methyl}- 1H-1,2,3-triazole-4-carboxamide::US10344025, Example 400::US11370786, Example 400

SMILES Cc1ccc(CC(=O)Nc2cn(CC(F)CCn3cc(nn3)C(=O)NCc3cc(ccn3)C(F)(F)F)nn2)cn1

InChI Key InChIKey=HPKMMSCNDQFHIO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405056   

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM405056(US10344025, Example 400 | 1-(3-fluoro-4-{4-[2-(6-m...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM405056(US10344025, Example 400 | 1-(3-fluoro-4-{4-[2-(6-m...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent