BDBM405046 1-(4-{4-[2-(3,3-difluoroazetidin-1- yl)acetamido]-1H-1,2,3-triazol-1-yl}- 3-fluorobutyl)-N-{[2-fluoro-5- (trifluoromethoxy)phenyl]methyl}- 1H-1,2,3-triazole-4-carboxamide::US10344025, Example 390::US11370786, Example 390

SMILES FC(CCn1cc(nn1)C(=O)NCc1cc(OC(F)(F)F)ccc1F)Cn1cc(NC(=O)CN2CC(F)(F)C2)nn1

InChI Key InChIKey=MVTXNLVSAMCLPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405046   

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM405046(US10344025, Example 390 | 1-(4-{4-[2-(3,3-difluoro...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM405046(US10344025, Example 390 | 1-(4-{4-[2-(3,3-difluoro...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent