BDBM405038 1-[4-(4-{2-[2-fluoro-5- (trifluoromethoxy)phenyl]acetamido} 1H-1,2,3-triazol-1-yl)butyl]-N-[(3- fluoropyridin-2-yl)methyl]-1H-1,2,3- triazole-4-carboxamide::US10344025, Example 382::US11370786, Example 382

SMILES Fc1ccc(OC(F)(F)F)cc1CC(=O)Nc1cn(CCCCn2cc(nn2)C(=O)NCc2ncccc2F)nn1

InChI Key InChIKey=TZZNVHRJHAUSAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405038   

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM405038(US10344025, Example 382 | 1-[4-(4-{2-[2-fluoro-5- ...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM405038(US10344025, Example 382 | 1-[4-(4-{2-[2-fluoro-5- ...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent