BDBM404763 1-[4-(4-{[(2-chloro-5- fluorophenyl)methyl]carbamoyl}- 1H-1,2,3-triazol-1-yl)butyl]-N- {[4-(trifluoromethyl)pyridin-2- yl]methyl}-1H-1,2,3-triazole-4- carboxamide::US10344025, Example 107::US11370786, Example 107

SMILES Fc1ccc(Cl)c(CNC(=O)c2cn(CCCCn3cc(nn3)C(=O)NCc3cc(ccn3)C(F)(F)F)nn2)c1

InChI Key InChIKey=QZUKMUWUHVNFNC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404763   

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404763(1-[4-(4-{[(2-chloro-5- fluorophenyl)methyl]carbamo...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404763(1-[4-(4-{[(2-chloro-5- fluorophenyl)methyl]carbamo...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent