BDBM404761 1-[4-(4-{[(3- cyclopropylphenyl)methyl] carbamoyl}-1H-1,2,3-triazol- 1-yl)butyl]-N-{[4- (trifluoromethyl)pyridin-2- yl]methyl}-1H-1,2,3-triazole- 4-carboxamide::US10344025, Example 105::US11370786, Example 105

SMILES FC(F)(F)c1ccnc(CNC(=O)c2cn(CCCCn3cc(nn3)C(=O)NCc3cccc(c3)C3CC3)nn2)c1

InChI Key InChIKey=ASYDEZOQHPYVGI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404761   

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404761(1-[4-(4-{[(3- cyclopropylphenyl)methyl] carbamoyl}...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404761(1-[4-(4-{[(3- cyclopropylphenyl)methyl] carbamoyl}...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent