BDBM404729 US10344025, Example 73::US11370786, Example 73::tert-butyl 3-{[(5-{4-[4-({[3- (trifluoromethoxy)phenyl]methyl} carbamoyl)-1H-1,2,3-triazol-1-yl] butyl}-1,3,4-thiadiazol-2- yl)formamido]methyl}azetidine-1- carboxylate

SMILES CC(C)(C)OC(=O)N1CC(CNC(=O)c2nnc(CCCCn3cc(nn3)C(=O)NCc3cccc(OC(F)(F)F)c3)s2)C1

InChI Key InChIKey=QLQKVNMNEFYPCT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404729   

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404729(tert-butyl 3-{[(5-{4-[4-({[3- (trifluoromethoxy)ph...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404729(tert-butyl 3-{[(5-{4-[4-({[3- (trifluoromethoxy)ph...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent