BDBM404712 2-methylpropyl N-[(1-{4-[4-({[3- (trifluoromethoxy)phenyl] methyl}carbamoyl)-1H-1,2,3- triazol-1-yl]butyl}-1H-1,2,3- triazol-4-yl)methyl]carbamate::US10344025, Example 56::US11370786, Example 56

SMILES CC(C)COC(=O)NCc1cn(CCCCn2cc(nn2)C(=O)NCc2cccc(OC(F)(F)F)c2)nn1

InChI Key InChIKey=WFMGWVIZAUHBIV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404712   

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404712(2-methylpropyl N-[(1-{4-[4-({[3- (trifluoromethoxy...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
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TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404712(2-methylpropyl N-[(1-{4-[4-({[3- (trifluoromethoxy...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent