BDBM404691 N-benzyl-5-(4-{6-[2-(pyridin-3- yl)acetamido]pyridazin-3-yl} butyl)-1,3,4-thiadiazole-2- carboxamide::US10344025, Example 30::US11370786, Example 30

SMILES O=C(Cc1cccnc1)Nc1ccc(CCCCc2nnc(s2)C(=O)NCc2ccccc2)nn1

InChI Key InChIKey=GGKKPKBJZKUKPG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404691   

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404691(N-benzyl-5-(4-{6-[2-(pyridin-3- yl)acetamido]pyrid...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
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TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404691(N-benzyl-5-(4-{6-[2-(pyridin-3- yl)acetamido]pyrid...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent