BDBM404690 N-benzyl-5-(4-{6-[(2S)-2- hydroxy-2-phenylacetamido] pyridazin-3-yl}butyl)-1,3,4- thiadiazole-2-carboxamide::US10344025, Example 29::US11370786, Example 29

SMILES O[C@H](C(=O)Nc1ccc(CCCCc2nnc(s2)C(=O)NCc2ccccc2)nn1)c1ccccc1

InChI Key InChIKey=RSMULVZOMKYBMS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404690   

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404690(N-benzyl-5-(4-{6-[(2S)-2- hydroxy-2-phenylacetamid...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
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TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404690(N-benzyl-5-(4-{6-[(2S)-2- hydroxy-2-phenylacetamid...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent