BDBM404684 N-[(1S)-2-hydroxy-1- phenylethyl]-1-[4-(5-{2-[3- (trifluoromethoxy)phenyl] acetamido}-1,3,4-thiadiazol- 2-yl)butyl]-1H-1,2,3- triazole-4-carboxamide::US10344025, Example 23::US11370786, Example 23

SMILES OC[C@@H](NC(=O)c1cn(CCCCc2nnc(NC(=O)Cc3cccc(OC(F)(F)F)c3)s2)nn1)c1ccccc1

InChI Key InChIKey=JRXBVSWLZJNDND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404684   

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404684(N-[(1S)-2-hydroxy-1- phenylethyl]-1-[4-(5-{2-[3- (...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404684(N-[(1S)-2-hydroxy-1- phenylethyl]-1-[4-(5-{2-[3- (...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent