BDBM404680 N-(pyridin-2-ylmethyl)-1-[4- (5-{2-[3-(trifluoromethoxy) phenyl]acetamido}-1,3,4- thiadiazol-2-yl)butyl]-1H-1,2,3- triazole-4-carboxamide::US10344025, Example 19::US11370786, Example 19

SMILES FC(F)(F)Oc1cccc(CC(=O)Nc2nnc(CCCCn3cc(nn3)C(=O)NCc3ccccn3)s2)c1

InChI Key InChIKey=HACCQHWRPXDDBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404680   

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404680(N-(pyridin-2-ylmethyl)-1-[4- (5-{2-[3-(trifluorome...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404680(N-(pyridin-2-ylmethyl)-1-[4- (5-{2-[3-(trifluorome...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent