BDBM404672 N-(cyclopropylmethyl)-1-[4- (5-{2-[3-(trifluoromethoxy) phenyl]acetamido}-1,3,4- thiadiazol-2-yl)butyl]-1H- 1,2,3-triazole-4-carboxamide::US10344025, Example 11::US11370786, Example 11

SMILES FC(F)(F)Oc1cccc(CC(=O)Nc2nnc(CCCCn3cc(nn3)C(=O)NCC3CC3)s2)c1

InChI Key InChIKey=IGYJVOAZKNQHDC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404672   

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404672(N-(cyclopropylmethyl)-1-[4- (5-{2-[3-(trifluoromet...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
The University of Texas System

US Patent
LigandPNGBDBM404672(N-(cyclopropylmethyl)-1-[4- (5-{2-[3-(trifluoromet...)
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent