BDBM404656 US10344000, Example 17A

SMILES O[C@@H]1CN(CCC1C(O)=O)c1nn(C(=O)c2c(Cl)cccc2C2CC2)c2CCCCc12

InChI Key InChIKey=IOGNNGFDGJQIKR-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 404656   

TargetNuclear receptor ROR-gamma(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM404656(US10344000, Example 17A)Copy SMILESCopy InChI

Affinity DataIC50: 19nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/9/2020
Entry Details
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