BDBM404645 US10344000, Example 9A

SMILES C[C@@]1(CO)CCc2c(C1)n(nc2C1=CCC(CC1)C([O-])=O)C(=O)c1c(Cl)cccc1C1CC1

InChI Key InChIKey=RWYIYHBLOVRAEE-UHFFFAOYSA-M

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 404645   

TargetNuclear receptor ROR-gamma(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM404645(US10344000, Example 9A)Copy SMILESCopy InChI

Affinity DataIC50: 3.99E+3nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/9/2020
Entry Details
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