BDBM404634 US10344000, Example 3A

SMILES CC1CCCc2c1c(nn2C(=O)c1c(Cl)cccc1C1CC1)[C@@]1(CCC=CC1)C(O)=O

InChI Key InChIKey=RBDSGZPCMYVLSM-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 404634   

TargetNuclear receptor ROR-gamma(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM404634(US10344000, Example 3A)Copy SMILESCopy InChI

Affinity DataIC50: 1.81E+3nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/9/2020
Entry Details
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