BDBM404627 4-(1-{[2-chloro-6-(1- cyanocyclobutyl) phenyl]carbonyl}- 1,4,5,6- tetrahydrocyclopenta [c]pyrazol-3- yl)cyclohex-3-ene-1- carboxylic acid::US10344000, Example 1F

SMILES OC(=O)C1CCC(=CC1)c1nn(C(=O)c2c(Cl)cccc2C2(CCC2)C#N)c2CCCc12

InChI Key InChIKey=ZXXIVUWQPBTAFL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 404627   

TargetNuclear receptor ROR-gamma(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM404627(4-(1-{[2-chloro-6-(1- cyanocyclobutyl) phenyl]carb...)
Affinity DataIC50: 1.17E+3nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details
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