BDBM40457 3-(4-chlorophenyl)-5-methyl-6-(phenylmethyl)-2-(trifluoromethyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one::6-benzyl-3-(4-chlorophenyl)-5-methyl-2-(trifluoromethyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one::CHEMBL522818::UNM000003620201::cid_2211071

SMILES Cc1nc2c(c([nH]n2c(=O)c1Cc1ccccc1)C(F)(F)F)-c1ccc(Cl)cc1

InChI Key InChIKey=NAEVADOJZKGAGC-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 40457   

TargetN-formyl peptide receptor 2(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM40457(cid_2211071 | UNM000003620201 | CHEMBL522818 | 3-(...)
Affinity DataIC50: 6.67E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2011
Entry Details
PCBioAssay
TargetfMet-Leu-Phe receptor(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM40457(cid_2211071 | UNM000003620201 | CHEMBL522818 | 3-(...)
Affinity DataIC50: 3.80E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2011
Entry Details
PCBioAssay
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM40457(cid_2211071 | UNM000003620201 | CHEMBL522818 | 3-(...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetfMet-Leu-Phe receptor(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM40457(cid_2211071 | UNM000003620201 | CHEMBL522818 | 3-(...)
Affinity DataKi:  2.50E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2011
Entry Details
PCBioAssay
TargetN-formyl peptide receptor 2(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM40457(cid_2211071 | UNM000003620201 | CHEMBL522818 | 3-(...)
Affinity DataKi: >4.03E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2011
Entry Details
PCBioAssay