BDBM404354 3'-chloro-N-(1-cyanopyrrolidin-3- yl)-[1,1'-biphenyl]-4-carboxamide::US10343992, Example 13::US10689345, Example 13::US11066365, Example 13

SMILES Clc1cccc(c1)-c1ccc(cc1)C(=O)NC1CCN(C1)C#N

InChI Key InChIKey=VVEVWXPBSKUVRO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 404354   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Missions Therapeutics

US Patent
LigandPNGBDBM404354(3'-chloro-N-(1-cyanopyrrolidin-3- yl)-[1,1'-biphen...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Missions Therapeutics

US Patent
LigandPNGBDBM404354(3'-chloro-N-(1-cyanopyrrolidin-3- yl)-[1,1'-biphen...)
Affinity DataIC50: 100nMAssay Description:USP30 Biochemical Fluorescence Intensity Kinetic Assay.Reactions were performed in duplicate in black 384 well plates (small volume, Greiner 784076) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Missions Therapeutics

US Patent
LigandPNGBDBM404354(3'-chloro-N-(1-cyanopyrrolidin-3- yl)-[1,1'-biphen...)
Affinity DataIC50: 100nMAssay Description:USP30 biochemical fluorescence intensity IC50 assay Dilution plates were prepared at 21 times the final concentration (2100 μM for a final conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2021
Entry Details
Go to US Patent