BDBM404272 US10017501, Compound 1020-75

SMILES Cc1n[nH]c(C)c1-c1cc(cc2[nH]c(nc12)C1CCC1)-c1c(C)noc1C

InChI Key InChIKey=AGIUJEIARSZHNL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404272   

TargetBromodomain-containing protein 4 [75-147](Human)
Gilead Sciences

US Patent
LigandPNGBDBM404272(US10017501, Compound 1020-75)
Affinity DataIC50: 121nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [368-440](Human)
Gilead Sciences

US Patent
LigandPNGBDBM404272(US10017501, Compound 1020-75)
Affinity DataIC50: 78.2nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
Go to US Patent