BDBM403411 US10335392, Example 18

SMILES CN1CCN(CC1)c1ncc(cn1)-c1cc2n3[C@@H]([C@@H]4C[C@@H]4c3nc2cc1F)c1ccccc1OC(F)F

InChI Key InChIKey=SWSIXVRBDBKKTP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 403411   

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM403411(US10335392, Example 18)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (LABCYTE, Cat. # LP-0200) at final concentrations ranging from 0.004 μM to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
Go to US Patent