BDBM403385 US10329320, Compound 73

SMILES COC[C@]12CC[C@@](C)(O)C[C@H]1CC[C@H]1[C@@H]3CCC(C(O)Cn4nnc(C)n4)[C@@]3(C)CC[C@H]21

InChI Key InChIKey=QNSSUZNWKLOYST-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 403385   

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM403385(US10329320, Compound 73)
Affinity DataIC50: 30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
Go to US Patent