BDBM403368 US10329320, Compound 49::US11124538, Compound 49

SMILES COC[C@]12CC[C@@](C)(O)C[C@@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)Cn4ncc5ccc(OC)cc45)[C@@]3(C)CC[C@H]21

InChI Key InChIKey=TVAZUCDAYFAZGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403368   

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM403368(US10329320, Compound 49 | US11124538, Compound 49)
Affinity DataIC50: 75nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
Go to US Patent

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM403368(US10329320, Compound 49 | US11124538, Compound 49)
Affinity DataIC50: 75nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent