BDBM402789 2-(3,8- diazabicyclo[3.2.1]oct-8- yl)-N-[1-methyl-3- (trifluoromethyl)-1H- pyrazol-4-yl]pyrrolo[2,1- f][1,2,4]triazine-7- carboxamide trifluoroacetate::US10329295, Example 96

SMILES Cn1cc(NC(=O)c2ccc3cnc(nn23)N2C3CCC2CNC3)c(n1)C(F)(F)F

InChI Key InChIKey=QFHUVZUGQYGQLM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402789   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402789(US10329295, Example 96 | 2-(3,8- diazabicyclo[3.2....)
Affinity DataIC50: 5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
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