BDBM402695 2-[(3R)-3-aminopiperidin- 1-yl]-N-[3- (difluoromethyl)-1- methyl-1H-pyrazol-4- yl]pyrrolo[2,1- f][1,2,4]triazine-7- carboxamide trifluoroacetate::US10329295, Example 18

SMILES Cn1cc(NC(=O)c2ccc3cnc(nn23)N2CCC[C@@H](N)C2)c(n1)C(F)F

InChI Key InChIKey=IDKXEIVFCNJSDV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402695   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402695(US10329295, Example 18 | 2-[(3R)-3-aminopiperidin-...)
Affinity DataIC50: 0.5nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
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Date in BDB:
5/31/2020
Entry Details
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