BDBM402343 US10329282, Compound TDI01221::US11390609, Compound TDI01221

SMILES CN(C)c1ccc(NC(=O)c2cc3ccc(cc3[nH]2)-c2nccc(Nc3ccc4[nH]ncc4c3)n2)cn1

InChI Key InChIKey=BOFCSNMZBAYRQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 402343   

TargetRho-associated protein kinase 2 [1-119](Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM402343(US10329282, Compound TDI01221 | US11390609, Compou...)
Affinity DataIC50: 91nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
Go to US Patent

TargetRho-associated protein kinase 2(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM402343(US10329282, Compound TDI01221 | US11390609, Compou...)
Affinity DataIC50: 91nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent