BDBM402314 US10329282, Compound TDI01136::US11390609, Compound TDI01136

SMILES CC(C)NC(=O)c1cc2ccc(cc2s1)-c1nc(Nc2ccc3[nH]ncc3c2)c2sccc2n1

InChI Key InChIKey=NFXGDALNXMWYCR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 402314   

TargetRho-associated protein kinase 2 [1-119](Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM402314(US10329282, Compound TDI01136 | US11390609, Compou...)
Affinity DataIC50: 66nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
Go to US Patent

TargetRho-associated protein kinase 1(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM402314(US10329282, Compound TDI01136 | US11390609, Compou...)
Affinity DataIC50: 827nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent

TargetRho-associated protein kinase 2(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM402314(US10329282, Compound TDI01136 | US11390609, Compou...)
Affinity DataIC50: 66nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent