BDBM402191 (9aS)-7-[2,6-difluoro-4-(2- phenylethynyl)phenyl]-9a-methyl- 2-(1-methyl-6-oxo-3-pyridyl)- 4,9-dihydro-3H-pyrazino[1,2- c]pyrimidine-1,6,8-trione::US10011607, 24

SMILES Cn1cc(ccc1=O)N1CCN2C(=O)N(C(=O)C[C@@]2(C)C1=O)c1c(F)cc(cc1F)C#Cc1ccccc1

InChI Key InChIKey=AVOXVZFVGVVPKP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402191   

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM402191(US10011607, 24 | (9aS)-7-[2,6-difluoro-4-(2- pheny...)
Affinity DataEC50:  128nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
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