BDBM402169 (9aRS)-7-[2,6-difluoro-4-(2- phenylethynyl)phenyl]-2- (2-pyridyl)- 3,4,9,9a-tetrahydropyrazino[1,2- c]pyrimidine-1,6,8-trione::US10011607, 3

SMILES Fc1cc(cc(F)c1N1C(=O)CC2N(CCN(C2=O)c2ccccn2)C1=O)C#Cc1ccccc1

InChI Key InChIKey=XWCVWNPRBSIUOL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402169   

TargetMetabotropic glutamate receptor 4(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM402169(US10011607, 3 | (9aRS)-7-[2,6-difluoro-4-(2- pheny...)
Affinity DataEC50:  235nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
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