BDBM402054 N-(2-((4,6-dimethylpyrimidin-2- yl)(methyl)amino)ethyl)-N-ethyl-4- fluoro-2-(2H-1,2,3-triazol-2- yl)benzamide::US10011595, B-12

SMILES CCN(CCN(C)c1nc(C)cc(C)n1)C(=O)c1ccc(F)cc1-n1nccn1

InChI Key InChIKey=JVEQWXPKUYMQAY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 402054   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402054(US10011595, B-12 | N-(2-((4,6-dimethylpyrimidin-2-...)
Affinity DataIC50: 12.6nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402054(US10011595, B-12 | N-(2-((4,6-dimethylpyrimidin-2-...)
Affinity DataIC50: 2.83E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent