BDBM401874 2-{1-[(3R,6R)-6-Methyl-1-{[2-(1H- pyrazol-1-yl)pyridin-3- yl]carbonyl}piperidin-3-yl]-1H- pyrazol-4-yl}propan-2-ol::US10010539, 90

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1cccnc1-n1cccn1)n1cc(cn1)C(C)(C)O

InChI Key InChIKey=DHSHERCUNIPCCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 401874   

TargetOrexin/Hypocretin receptor type 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM401874(US10010539, 90 | 2-{1-[(3R,6R)-6-Methyl-1-{[2-(1H-...)
Affinity DataIC50: 33.6nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM401874(US10010539, 90 | 2-{1-[(3R,6R)-6-Methyl-1-{[2-(1H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent