BDBM401853 2-(2-{(3R,6R)-1-[(2- Ethoxyphenyl)carbonyl]-6- methylpiperidin-3-yl}-5-methyl- 2H-1,2,3-triazol-4-yl)propan-2-ol::US10010539, 69

SMILES CCOc1ccccc1C(=O)N1C[C@@H](CC[C@H]1C)n1nc(C)c(n1)C(C)(C)O

InChI Key InChIKey=PCTSOLDNZSVKNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 401853   

TargetOrexin/Hypocretin receptor type 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM401853(US10010539, 69 | 2-(2-{(3R,6R)-1-[(2- Ethoxyphenyl...)
Affinity DataIC50: 7.90nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM401853(US10010539, 69 | 2-(2-{(3R,6R)-1-[(2- Ethoxyphenyl...)
Affinity DataIC50: 1.95E+3nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent