BDBM401837 2-{2-[(3R,6R)-6-methyl-1-{[2-methyl-6- (2H-1,2,3-triazol-2- yl)phenyl]carbonyl}piperidin-3-yl]-2H- 1,2,3-triazol-4-yl}propan-2-ol::US10010539, 53

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1c(C)cccc1-n1nccn1)n1ncc(n1)C(C)(C)O

InChI Key InChIKey=SWVYZADIKLPYFC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 401837   

TargetOrexin/Hypocretin receptor type 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM401837(US10010539, 53 | 2-{2-[(3R,6R)-6-methyl-1-{[2-meth...)
Affinity DataIC50: 31.1nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM401837(US10010539, 53 | 2-{2-[(3R,6R)-6-methyl-1-{[2-meth...)
Affinity DataIC50: 1.81E+3nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent