BDBM401526 (S)-2-(4-(4-chloro-2-(1-methyl- 1H-pyrazol-5- yl)phenoxy)phenyl)-6-((2- oxopyrrolidin-3-yl)amino)- pyrimidine-4-carboxamide::US10005768, Compound 141

SMILES Cn1nccc1-c1cc(Cl)ccc1Oc1ccc(cc1)-c1nc(N[C@H]2CCNC2=O)cc(n1)C(N)=O

InChI Key InChIKey=RWIRTQCZAKPWSF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 401526   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM401526(US10005768, Compound 141 | (S)-2-(4-(4-chloro-2-(1...)
Affinity DataIC50: 450nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
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