BDBM401512 6-(2-(1H-imidazol-1-yl)ethyl)-2- (4-(2-(morpholinomethyl)-4- (trifluoromethyl)phenoxy)phenyl) pyrimidine-4-carboxamide::US10005768, Compound 127

SMILES NC(=O)c1cc(CCn2ccnc2)nc(n1)-c1ccc(Oc2ccc(cc2CN2CCOCC2)C(F)(F)F)cc1

InChI Key InChIKey=QWBXMHXJKJUMFV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 401512   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM401512(US10005768, Compound 127 | 6-(2-(1H-imidazol-1-yl)...)
Affinity DataIC50: 486nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
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