BDBM401394 US10005762, Example 74

SMILES CCCCCc1cc(C[C@@](O)([C@@H](N)CC(C)C)C(O)=O)ncc1C

InChI Key InChIKey=IJPDDPYURZYUSM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 401394   

TargetLeucyl-cystinyl aminopeptidase(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM401394(US10005762, Example 74)
Affinity DataIC50: 3.20nMAssay Description:The inventors have assumed that inhibition of nocturnal activity of placental leucine aminopeptidase (P-LAP), i.e. aminopeptidase that cleaves AVP, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandPNGBDBM401394(US10005762, Example 74)
Affinity DataIC50: 2.60nMAssay Description:The inventors have assumed that inhibition of nocturnal activity of placental leucine aminopeptidase (P-LAP), i.e. aminopeptidase that cleaves AVP, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent