BDBM401372 US10005762, Example 52

SMILES CC(C)C[C@H](N)[C@](O)(Cc1nccc2C[C@@H](CCC3CC3)Cc12)C(O)=O

InChI Key InChIKey=PXESZBHBYSOLEN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 401372   

TargetLeucyl-cystinyl aminopeptidase(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM401372(US10005762, Example 52)
Affinity DataIC50: 5.90nMAssay Description:The inventors have assumed that inhibition of nocturnal activity of placental leucine aminopeptidase (P-LAP), i.e. aminopeptidase that cleaves AVP, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetLeucyl-cystinyl aminopeptidase(Human)
Astellas Pharma

US Patent
LigandPNGBDBM401372(US10005762, Example 52)
Affinity DataIC50: 4.90nMAssay Description:The inventors have assumed that inhibition of nocturnal activity of placental leucine aminopeptidase (P-LAP), i.e. aminopeptidase that cleaves AVP, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent