BDBM401008 US10005735, Compound 17

SMILES Fc1ccc(CNC(=O)c2cnc3c(S)cccc3c2)cc1

InChI Key InChIKey=DSFOANBRLABAIJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 401008   

Target26S proteasome non-ATPase regulatory subunit 14(Human)
California Institute of Technology

US Patent
LigandPNGBDBM401008(US10005735, Compound 17)
Affinity DataIC50: 200nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
California Institute of Technology

US Patent
LigandPNGBDBM401008(US10005735, Compound 17)
Affinity DataIC50: 1.80E+4nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetAMSH-like protease(Human)
California Institute of Technology

US Patent
LigandPNGBDBM401008(US10005735, Compound 17)
Affinity DataIC50: 850nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent