BDBM400990 US10005735, Compound 3

SMILES COC(=O)CNC(=O)c1cnc2c(S)cccc2c1

InChI Key InChIKey=BJSBCYUOXXELFZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 400990   

Target26S proteasome non-ATPase regulatory subunit 14(Human)
California Institute of Technology

US Patent
LigandPNGBDBM400990(US10005735, Compound 3)
Affinity DataIC50: 2.80E+3nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
California Institute of Technology

US Patent
LigandPNGBDBM400990(US10005735, Compound 3)
Affinity DataIC50: 1.20E+5nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetAMSH-like protease(Human)
California Institute of Technology

US Patent
LigandPNGBDBM400990(US10005735, Compound 3)
Affinity DataIC50: 2.20E+3nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent