BDBM400834 6'-((1,3,5-triazin-2-yl)amino)-8'-chloro-2'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'-dione (Cpd. No. 11)::US10000487, Example 11

SMILES Clc1cc(Nc2ncncn2)c(=O)n2c1C(=O)NC21CCCCC1

InChI Key InChIKey=WYDINWOAGJJFPJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 400834   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM400834(6'-((1,3,5-triazin-2-yl)amino)-8'-chloro-2'H-spiro...)
Affinity DataIC50: 10nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent