BDBM400830 8'-chloro-6'-((2-methyl-2H-1,2,3-triazol-4-yl)amino)-2'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'-dione (Cpd. No. 7)::US10000487, Example 7

SMILES Cn1ncc(Nc2cc(Cl)c3C(=O)NC4(CCCCC4)n3c2=O)n1

InChI Key InChIKey=FIUIAJSGWHARNQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 400830   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM400830(8'-chloro-6'-((2-methyl-2H-1,2,3-triazol-4-yl)amin...)
Affinity DataIC50: 10nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent