BDBM400721 US10000476, Compound I-80

SMILES Cc1cccc(Oc2ccc(cc2)C2(Cn3cccc(C)c3=O)NC(=O)NC2=O)c1

InChI Key InChIKey=SDVXKQYCSZMWIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 400721   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Kaken Pharmaceutical

US Patent
LigandPNGBDBM400721(US10000476, Compound I-80)
Affinity DataIC50: 100nMAssay Description:The TACE inhibition test was carried out by measuring TACE activity in the presence and the absence of the test substance using the thus-obtained TAC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent