BDBM4007 1 H-indole-3-alkanamide deriv. 10p::2,2 -Dithiobis[alpha-(acety1amino)-N-(phenylmethyl)-1H-indole-3-propanamide]: Isolation of Diastereoisomer Pairs::N-benzyl-3-[2-({3-[2-(benzylcarbamoyl)-2-acetamidoethyl]-1H-indol-2-yl}disulfanyl)-1H-indol-3-yl]-2-acetamidopropanamide

SMILES CC(=O)NC(Cc1c(SSc2[nH]c3ccccc3c2CC(NC(C)=O)C(=O)NCc2ccccc2)[nH]c2ccccc12)C(=O)NCc1ccccc1

InChI Key InChIKey=MTTNYIXYAZMASA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4007   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4007(N-benzyl-3-[2-({3-[2-(benzylcarbamoyl)-2-acetamido...)
Affinity DataIC50: 5.10E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
University of Auckland

LigandPNGBDBM4007(N-benzyl-3-[2-({3-[2-(benzylcarbamoyl)-2-acetamido...)
Affinity DataIC50: 500nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2005
Entry Details Article
PubMed