BDBM400645 US10000476, Compound I-4::US10000476, Compound I-60

SMILES COc1cccc(c1)C1(Cn2cccc(C)c2=O)NC(=O)NC1=O

InChI Key InChIKey=AVBKGXCIBYLDOQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 400645   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Kaken Pharmaceutical

US Patent
LigandPNGBDBM400645(US10000476, Compound I-60 | US10000476, Compound I...)
Affinity DataIC50: 100nMAssay Description:The TACE inhibition test was carried out by measuring TACE activity in the presence and the absence of the test substance using the thus-obtained TAC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Kaken Pharmaceutical

US Patent
LigandPNGBDBM400645(US10000476, Compound I-60 | US10000476, Compound I...)
Affinity DataIC50: 550nMAssay Description:The TACE inhibition test was carried out by measuring TACE activity in the presence and the absence of the test substance using the thus-obtained TAC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent