BDBM400607 US9999624, 6

SMILES NC1=N[C@]2(CN(C[C@H]2CS1)c1ncc(F)cn1)c1cccc(NC(=O)c2ccc(cn2)C#N)c1

InChI Key InChIKey=YTAZIODAUBSVFU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 400607   

TargetBeta-secretase 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM400607(US9999624, 6)
Affinity DataIC50: 0.450nMAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20× in KH2PO4 buffer. Ten μL of each dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent