BDBM400245 US10329273, Example 16::US11479538, Example 16

SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccn(CC3CCC3)n2)=C(C(=O)N1)n1nn[nH]c1=O)C(F)(F)F

InChI Key InChIKey=JGMOZJFBAVTQDX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 400245   

LigandPNGBDBM400245(US10329273, Example 16 | US11479538, Example 16)
Affinity DataIC50: 5nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

Target2-acylglycerol O-acyltransferase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM400245(US10329273, Example 16 | US11479538, Example 16)
Affinity DataIC50: 5nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent